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ATP dimagnesium
CAS No. 74804-12-9
ATP dimagnesium( —— )
Catalog No. M36632 CAS No. 74804-12-9
ATP dimagnesium is an important substance for energy storage and metabolism in the body and is involved in the energy cycle and metabolism of the body.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | In Stock |
|
| 100MG | 36 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameATP dimagnesium
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NoteResearch use only, not for human use.
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Brief DescriptionATP dimagnesium is an important substance for energy storage and metabolism in the body and is involved in the energy cycle and metabolism of the body.
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DescriptionATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation.
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In VitroATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.ATP promotes neutrophil chemotaxis in vitro.
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In VivoATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.Animal Model:Four-week-old Kunming mice (18-22 g)Dosage:50 mg/kg Administration: Intraperitoneal injection, before bacterial (E. coli) challenge Result:Protected mice from bacterial infection.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number74804-12-9
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Formula Weight551.76
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Molecular FormulaC10H12Mg2N5O13P3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 250 mg/mL (453.10 mM; Ultrasonic)
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SMILES[Mg++].[Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8.?
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